The fifth season of the American television series Agents of S.H.I.E.L.D., based on the Marvel Comics organization S.H.I.E.L.D. (Strategic Homeland Intervention, Enforcement, and Logistics Division), revolves around the character of Phil Coulson and other S.H.I.E.L.D. agents and allies as they try to save humanity while in deep space. It is set in the Marvel Cinematic Universe (MCU), sharing continuity with the films of the franchise.